Tristan Da Cunha, South Atlantic Ocean
The most distant human settlement on Earth is Tristan Da Cunha, a volcanic island in the South Atlantic Ocean. Tristan Da Cunha, one of five islands in its name, is 1,750 miles from Cape Town, South Africa, and 38 square miles.
Pitcairn Islands, Southern Pacific Ocean
The British Overseas Territories include the four volcanic Pitcairn Islands in the Southern Pacific Ocean. Only Pitcairn Island, a two-square-mile island, is inhabited.
Easter Island, Chile
Easter Island, or Rapa Nui, is officially part of Chile despite being 2,200 miles off the coast. More than 2,600 miles from Tahiti (from where many visitors go), 1,200 miles from Pitcairn Island, and 1,600 miles from Mangareva
Devon Island, Canada
Devon Island (Tallurutit in Inuktitut) in Canada's Nunavut Territory is the world's biggest deserted island. Scientists have spent two decades believing it's Mars because of its cold, stony, and lonely nature.
Kerguelen Islands, Southern Indian Ocean
The very isolated Desolation Islands in the southern Indian Ocean are more than 2,000 kilometers from civilization. Grande Terre, the largest island in the French volcanic archipelago of 300 islands, is roughly the size of Delaware.
Ittoqqortoormiit, Greenland
Ittoqqortoormiit is frozen for nine months and nestled between Greenland's National Park (the world's biggest, 604,000 square miles) and Scoresby Sound (the world's largest fjord, 23,600 square miles).
Oymyakon, Russia
The next large city, Yakutsk, 576 miles distant, is further from the Arctic Circle than Oymyakon. This Siberian region is the coldest inhabited spot on Earth, with 500 tough residents.